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Description

Caryophyllene oxide is an oxygenated terpenoid, usually a metabolic by product of caryophyllene. It’s use as an antifungal is highly effective with certain species. In addition, caryophyllene oxide has also been indicated as an anticoagulant with platelets


Effects

Antifungal
Antocoagulant


Research

Antifungal

Commonly used as preservative in food, drugs, and cosmetics. Its antifungal activity has been compared to ciclopiroxolamine and sulconazole, mainly used in onychomycosis treatment and dermatophytes.
Use of caryophyllene oxide as an antifungal agent in an in vitro experimental model of onychomycosis.

Anticoagulant

Caryophyllene oxide isolated from the rhizome of Formosan Gynura japonica was shown to exhibit significant anti-platelet aggregation activity in vitro.
Anti-Platelet Aggregation and Chemical Constituents from the Rhizome of Gynura japonica